Address:

    Room #2423, Pharmacy Discipline, Academic Building #2, Khulna University, Sher-E-Bangla Road, Khulna-9208, Bangladesh

    Email:

    mmrahman0103@pharm.ku.ac.bd

    Contact:

    +880 1711 485602

    Personal Webpage:
    click here

Dr. Md. Mustafizur Rahman
Professor

Md. Mustafizur Rahman is a Professor of Pharmacy Discipline of Life Science School at Khulna University where he has been working as a faculty member since 2000. He served the Discipline as the Head of Pharmacy Discipline from March 23 2015 to March 22 2018. He received his B. Pharm. (Hon’s) & M. Pharm. degrees in Pharmacy from the University of Dhaka, Bangladesh. Right after completion of his study he started his career as Product Executive in a renowned Pharmaceutical Industry in Bangladesh. After acquiring professional experience from pharmaceutical industry Dr. Rahman joined Pharmacy Discipline of Khulna University as a faculty member.

He earned PhD degree in Medical Science from the University of Tokushima, Japan in 2009 with prestigious Monbukagakusho scholarship. His doctoral research entitled ‘Frequent overexpression of HMGA1 and 2 in gastroenteropancreatic neuroendocrine tumours and its relationship to let-7 downregulation’ was published in the British Journal of Cancer. He was also awarded Tokyo Biochemical Research Foundation (TBRF) fellowship to conduct two-year postdoctoral research in the Department of Cell Biology, Research Institute for Microbial Diseases of Osaka University, Japan. Dr. Rahman then came back to Bangladesh and joined Khulna University to serve the country. His research area was micro RNA mediated deregulation of oncogenes in cancer. His current research interests lie in the area of Molecular genetics of cancer with special focus on genetic polymorphism and cancer susceptibility. Recently he has published his work entitled ‘Genetic polymorphisms in CDH1 and Exo1 genes elevate the prostate cancer risk in Bangladeshi population in Breast Cancer. He received a grant from the Ministry of Science, Information and Technology, Bangladesh in 2015.  Dr. Rahman lives with his partner, a Dental Surgeon, and two school going kids.  Dr. Rahman is member of a number of professional organizations including, Bangladesh Society for Biochemistry and Molecular Biology (BSBMBB), Bangladesh Pharmaceutical Society, American Association of Cancer Research (AACR), Asian federation of Biotechnology (AFOB), Japanese Society for Molecular Biology, The Professional Society for Health Economics and Outcomes Research (ISPOR) etc. Very recently he attended the AACR Annual Meeting 2019 Atlanta in the USA held on March 27- April 3 and presented his research findings.

Bachelor of Pharmacy (Honors)

1994/May

Faculty of Pharmacy, the University of Dhaka, Bangladesh

 

Master of Pharmacy

(Thesis)

1997/February

Faculty of Pharmacy, The University of  Dhaka, Bangladesh

 

Doctor of Philosophy

(PhD in Medical Science.)

2009/March

Department of Human Pathology, Institute of Health Bio Sciences, The University of Tokushima, Japan

Postdoctoral Research

2010/10 to 2012/9

Department of Cell Biology, Research Institute for Microbial Diseases

Osaka University, Japan

# Pharmacogenomics: Association of genetic polymorphism especially single nucleotide polymorphisms (SNPs) with susceptibility, prognosis and treatment option in different types of human cancers

# Epigenetics: Role of miRNA in carcinogenesis and their possibility as therapeutic target

# Pharmacological evaluation of natural products from plant sources

Institute/University

Position

Responsibility

Tenure

 

Armed Forces Medical Institute, Dhaka, Bangladesh

 

Part time Instructor

Teaching

(Diploma in Pharmacy)

1996/6 to 1998/10

Pharmacy Discipline, Khulna University, Bangladesh

 

Lecturer

Research and Teaching

2000/5 to 2001/7

Pharmacy Discipline, Khulna University, Bangladesh

 

Assistant Professor

Research and Teaching

2001/7 to 2004/9

Graduate School of Medicine, The

University of Tokushima, Japan

Research Assistant

 

Research

2006/6  to 2008/12

Pharmacy Discipline, Khulna University, Bangladesh

Associate

Professor

 

Research and Teaching

2004/9 to 2010/02/14

Pharmacy Discipline, Khulna University, Bangladesh

Professor

 

Research and Teaching

2010/02/15 to date





Advanced Chemical Industries (ACI) Ltd, Dhaka, Bangladesh

Product Officer

Training and Product Management

1998/10 to 2000/5

 

 









List of Publication

2020

1.    Howlader, N.R., Rahman, M.M., Hossain, M.A., Sultana, R., Hossain, S.M., Mazid, M.A., Rahman, M.M. (2020) Genetic polymorphisms in DNA repair genes XRCC1 and 3 are associated with increased risk of breast cancer in Bangladeshi population. Breast Cancer Res Treat 182(2):739-750 https://doi.org/10.1007/s10549-020-05738-8

2019

2.       Islam, R., Adib, M., Ahsan, M., Rahman, M. M., & Mazid, M. A. (2019). Cholinesterase and Glycation Inhibition Assay of Several Metabolites Obtained from Plant and Fungi. Dhaka University Journal of Pharmaceutical Sciences, 18(1), 31-38. https://doi.org/10.3329/dujps.v18i1.41424

3.       Imtiaz, H., Afroz, S., Hossain, M. A., Bellah, S. F., Rahman, M. M., Kadir, M. S., Rahman, M. M. Genetic polymorphisms in CDH1 and Exo1 genes elevate the prostate cancer risk in Bangladeshi population, Tumor Biology. 2019, https://doi.org/10.1177/1010428319830837

4.       Mahaldar K, Hossain A, Islam F, Islam S, Islam MA, Shahriar M, Rahman MM. Antioxidant and hepatoprotective activity of Piper retrofractum against Paracetamol-induced hepatotoxicity in Sprague-Dawley rat, Natural Product Research, 2019 Jan 19:1-7, DOI: 10.1080/14786419.2018.1550768 (Short communication)

2018

5.       M.N.H. Zilani, M.G. Sarower, A. Hossain, A. Hossain, M.M. Rahman, S.J. Uddin, M.G. Hossain, Polymorphisms in cell cycle regulator gene P27KIP1 and P16INK4A and lung cancer risk in a Bangladeshi population. Pharmacologyonline, 2018, 2:149-160

6.       Ajijul Hakim Alif, Amir Hossain, Md. Akbar Hossain, Tabitha Mitali Madhu, Salma Akter Sumi and Md. Mustafizur Rahman*. Phytochemical and Pharmacological Evaluation of Cyperus odoratus Extract, Bangladesh Pharmaceutical Journal 2018. 21(2): 150-159, 2018 (July) ·  DOI:10.3329/bpj.v21i2.37927

2017

 

7.       Hasan M.M., Hossain A., Shamim A., Rahman M.M.* Phytochemical and pharmacological evaluation of ethanolic extract of Lepisanthes rubiginosa L. leaves, BMC Complementary and Alternative Medicine. BMC Complementary and Alternative Medicine (2017) 17:496 [DOI 10.1186/s12906-017-2010-y]

8.       Hossain, A., Murshid, G.M.M., Zilani, M.N.H., Islam F., Sultana R., Hossain M.G., Rahman M.M. TP53 codon72 polymorphism and breast cancer risk in Bangladeshi population.  Breast Cancer, 2017, 24(4), 571-578, doi:10.1007/s12282-016-0740-1

 

2016

 

9.       Sumi, S. A., Siraj, M. A.,Hossain, A., Mia,M. S., Afrin, S., Rahman, M. M., Investigation of the Key Pharmacological Activities of Ficusracemosa and Analysis of Its Major Bioactive Polyphenols by HPLC-DAD.Evidence-Based Complementary and Alternative Medicine, 2016, vol. 2016, Article ID 3874516, 9 pages, doi:10.1155/2016/3874516

10.   Hossain, A., Islam, F., Saifuzzaman, M., Saeed M.A.S., Islam, M.K., Murshid, G.M.M., and Rahman M.M. "Bioactivity of Boehmeria Macrophylla (Urticaceae) leaf extract. Orient Pharm Exp Med, 2016,16(3): 233-241. doi:10.1007/s13596-016-0230-1

11.   Mahaldar K., Saifuzzaman M., Irina T., Barman A.K, Islam A.K., Rahman M.M., Islam M.A. Analgesic, anthelmintic and toxicity studies of Solanum violaceum Linn. Leaves. Orient Pharm Exp Med, 2016, 16(2): 147-152 doi: 10.1007/s13596-016-0227-9

12.   Zilani, M.N.H., Islam, M.A., Khushi, S.S.,Shilpi J.A. Rahman M.M., Hossain, M.G., Analgesic and antioxidant activities of Colocasi afallax, Orient Pharm Exp Med, 2016, 16(2):131–137 DOI:10.1007/s13596-016-0222-1

2015

13. Islam F, Hossain A, Hossain MG, Murshid GMM, Rahman MM. Evaluation of Antioxidant, Analgesic and Cytotoxic Activities of T. angustata L. (Family– Typhaceae) Root. Dhaka Univ. J. Pharm. Sci. 2015 (June); 14(1): 53-59. https://doi.org/10.3329/dujps.v14i1.23736

14.   Khan MA, Islam MK, Siraj MA, Saha S, Barman AK, Awang K, Rahman MM, Shilpi JA, Jahan R, Islam E and Rahmatullah M, Ethnomedicinal survey of various communities residing in Garo Hills of Durgapur, Bangladesh. J EthnobiolEthnomed. 2015 May 30; 11(1): 44 (Epub ahead of print). DOI: 10.1186/s13002-015-0033-3

15.   Islam MK, Siraj MA, Sarker AB, Saha S, Mahmud I, Rahman MM. In-vitro anthelmintic activity of three Bangladeshi plants against Paramphistomumcervi and Haemonchuscontortus, Journal of Complementary & Integrative Medicine, 2015, 12(2):171-174, DOI: 10.1515/jcim-2014-0059.

16.  SmFaysalBellah, Md. IqubalHossainRaju, SM SakerBillah,ShaikhEmdadurRahman, G.M.M. Murshid, Md. Mustafizur Rahman, Evaluation of antibacterial and antidiarrhoeal activity of ethanolic extract of Feronialimonia Leaves. The Pharma Innovation Journal 2015; 3(11): 50-54.

2014

17.  Murshid GMM, Barman AK and Rahman MM, Evaluation of antioxidant, analgesic and cytotoxic activities of the aerial part of Cassia sophera L. (Caesalpiniaceae). International Journal of Phytopharmacology 2014; 5(5): 383-389.

18.   Sharmin Islam, Md. HasibulAlam, Md. Mustafizur Rahman, Shaikh Jamal Uddin, Sm Faysal Bellah, Gazi Md. Manjur Murshid. Anthelmintic and cytotoxic activity of the ethanolic extract of Phoenix sylvestris root. World J Pharm Sci 2014; 2(8):725-728

19.  Imran Mahmud, Md. Khirul Islam, SanjibSaha, Apurba Kumar Barman, Md. Mustafizur Rahman, Md. Anisuzzman, Taufiq Rahman, Abdullah Al-Nahain, Rownak Jahan and Mohammed Rahmatullah. Pharmacological and Ethnomedicinal overview of Heritierafomes: future prospects. International Scholarly Research Notices, Volume 2014, Article ID 938543, 12 pages, http://dx.doi.org/10.1155/2014/938543

20.  Md. Khirul Islam, Sanjib Saha, Imran Mahmud, KhalitMohamad, KhalijahAwang, Shaikh Jamal Uddin, Md. Mustafizur Rahman, Jamil A Shilpi. An ethnobotanical study of medicinal plants used by tribal and native people of Madhupur Forest Area, Bangladesh. Journal of Ethnopharmacology. 2014,151:921-30

2013

21.  Md. Saifuzzaman, Md. AwladHossain, Md. Anwar Hossain, Md. Amirul Islam, Gazi Md. MonjurMurshid and Md. Mustafizur Rahman, Cytotoxic and antibacterial activities of ethanolic extract of Leeaindica leaves. HamdardMedicus. 2013; 56(2): 12-19

22.   Mohammad Abdul MotalibMomin, SmFaysalBellah, MizanurRahaman Khan, Md. IqubalHossainRaju, Md. MustafizurRahman and AnjumanAra Begum. Phytopharmacological evaluation of ethanolic extract of Feronialimonia leaves. Am. J. Sci. Ind. Res., 2013, 4(5): 468-472 doi:10.5251/ajsir.2013.4.5.468.472

23.   M. M. Rahman, R. Sultana, M. R. Khan, M. A. Islam. Binding of Triprolidine Hydrochloride to Bovine Serum Albumin: Estimation of Binding parameters & Characterization of Binding Sites. Turk J Pharm Sci, 2013, 10(1), 49-56

2012

24.   M A. ISLAM, M. Saifuzzaman, F. Ahmed, M. M. Rahman, N. A. Sultana, K. Naher. Antinoceptive activity of methanolic extract of Acanthus Ilicifolius Linn. Leaves. 2012, Turk J Pharm Sci, 9(1): 51-60

25.   M. S. Islam Howlader, Md. MofizurRahman,Abul Bashar Ripon Khalipha, Firoj Ahmed and Md. Mustafizur Rahman. Antioxidant and antidiarrhoeal potentiality of Diospyrosblancoi. International Journal of Pharmacology, 2012, 8(5) :403-409 DOI: 10.3923/ijp.2012.403.409

URL: https://scialert.net/abstract/?doi=ijp.2012.403.409

2010

26.   M.A. Islam, S. Parvin, M. M. Rahman, M.I. Ahmed, N.N. Biswas, U.K. Karmakar and K. Naher. Phytochemical and biological investigation of seeds of Hyptissuaveolens. 2010, Khulna University Studies, 10 (1&2): 185-190

27.   Rahman MM, Qian ZR, Wang EL, Yoshimoto K, Nakasono M, Sultana R, Yoshida T, Hayashi T, Haba R, Ishida M, Okabe H, Sano T. DNA methyltransferases 1, 3a, and 3b overexpression and clinical significance in gastroenteropancreatic neuroendocrine tumors.HumPathol. 2010 Aug; 41(8):1069-78. PMID: 20381114 DOI: 10.1016/j.humpath.2010.01.011

28.   Wang EL, Qian ZR, Rahman MM, Yoshimoto K, Yamada S, Kudo E, Sano T.Increased expression of HMGA1 correlates with tumour invasiveness and proliferation in human pituitary adenomas. Histopathology, 2010 March ; 56(4):501-9 DOI: 10.1111/j.1365-2559.2010.03495.x

2009

29.   Wang EL, Qian ZR, Yamada S, Rahman MM, Inosita N, Kageji T, Endo H, Kudo E, Sano T. Clinicopathological characterization of TSH-producing adenomas: special reference to TSH-immunoreactive but clinically non-functioning adenomas. Endocr Pathol. 2009; 20(4):209-20. DOI: 10.1007/s12022-009-9094-y

30.   Rahman MM, Qian ZR, Wang EL, Sultana R, Kudo E, Nakasono M, Hayashi T, Kakiuchi S, Sano T.  Frequent overexpression of HMGA1 and 2 in gastroenteropancreatic neuroendocrine tumours and its relationship to let-7 downregulation. British Journal of Cancer, 2009 Feb 10;100(3):501-10. DOI: 10.1038/sj.bjc.6604883

31.   Qian ZR, Asa SL, Siomi H, Siomi MC, Yoshimoto K, Yamada S, Wang EL, Rahman MM, Inoue H, Itakura M, Kudo E, Sano T. Overexpression of HMGA2 relates to reduction of let-7 and its relationship to clinicopathological features in pituitary adenomas. Modern Pathology, 2009; 22(3):431-41 DOI: 10.1038/modpathol.2008.202

2008

32.   Abdul Kader Obari, Toshiaki Sano, KenitichiOyama, EijiKudo, Zhi R Qian